Determining Safe Dosing to Prevent Off-Target Toxicity

Time: 12:00 pm
day: Day One Track B AM


• Identifying whether the response is dose-dependent to avoid excessive drug application
• Examining preclinical data and pharmacodynamic activity to determine drug dosage and frequency whilst ensuring therapeutic safety
• Utilizing a priming dose for preliminary infusion to lower the initial toxicity of therapeutic
• Assessing possible areas for toxicity to occur beyond hematologic toxicity