Exosome Mediated Genetic Reprogramming of Tumor-Associated Macrophages

Time: 10:30 am
day: Day Two


• Engineered exosomes allow selective targeting of undruggable transcription factors in macrophages
• exoASO-STAT6 induces reprogramming of tumor-associated macrophages and promotes CD8 T-cell mediated adaptive immune responses
• exoASO-STAT6 shows potent monotherapy activity in several mouse syngeneic models