Douglas Wilson

Douglas Wilson

Company: Merck Research Laboratories

Job title: Principal Scientist


Development of MK-4830 (anti-ILT4 mAb) to Target Immunosuppressive Myeloid Cells for the Treatment of Human Malignancies 2:00 pm

MK-4830 is a fully human monoclonal antibody that targets ILT4 and blocks its binding to cognate ligands ILT4-blockade by MK-4830 alters the phenotype and function of myeloid-derived suppressor cells MK-4830 treatment induced tumor growth inhibition of a human cancer cell line in a humanized mouse model system MK-4830 and pembrolizumab combination therapy provides clinical benefit…Read more

day: Discovery & Pre-Clinical Development – Day 2 pm

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