Leonard Reyno

Company: Pionyr Immunotherapeutics

Job title: Chief Medical Officer

Bio:

Prior to joining Pionyr, Leonard Reyno was EVP and Chief Medical Officer at ORIC Pharmaceuticals leading the introduction of their first product candidate into human trials. Before that, he served as Senior Vice President and Chief Medical Officer at Agensys, a subsidiary of Astellas Pharma, where he led clinical stage development of multiple antibody products to novel targets through clinical proof of concept of multiple products. Dr. Reyno’s prior positions in industry included Global Medical Director for Taxotere/Breast cancer at Aventis, Medical Director and Lead Clinical Scientist for Herceptin at Genentech and Senior Director of Oncology at Cytokinetics. Before joining industry, Dr. Reyno was an academic oncologist, where he had both extensive experience as a clinician (especially in breast and genitor-urinary malignancy) as well as serving as Principal Investigator on multiple trials with the National Cancer Institute of Canada.

Seminars:

Depleting Tumor-associated Macrophages to Create an Immune Stimulatory Environment 2:00 pm

• Identify which population of immunosuppressive cells should be targeted to deplete • Outline the safety and toxicity potential of this type of strategy • Review the clinical translation opportunity of this therapy in combinationRead more

day: Day Two

Panel Discussion: Defining Metrics of Success with Macrophage-directed Therapeutics 9:30 am

Key questions to address: • What does success look like when manipulating macrophage phenotypes? • Is success defined through restructuring the tumor microenvironment or activating t cell infiltration to the tumor site? • What will be the most relevant strategy clinically addressing macrophages? • Define the most important parameters around this modality that will reflect…Read more

day: Day Two