Stuart Hughes

Stuart Hughes

Company: Pathios Therapeutics

Job title: Chief Executive Officer


Small Molecule GPR65 Inhibitors Reverse Acidosis-Induced Immunosuppression in Macrophages and Suppresses Tumor Growth in vivo Via an Elevation of Natural Killer (NK) Cells 1:30 pm

Solid tumors are typically more acidic than surrounding normal tissue  This acidity activates GPR65 on macrophages, causing a suppression pro-inflammatory cytokines and chemokines   Small molecule GPR65 inhibitors counteract this effect and reduce tumor growth in vivo through an increase in the infiltration of key effector cells Read more

day: Day One Track A PM

A Hanson Wade Group Company

© Copyright 2023 Hanson Wade | Design and site by Event Engine | Hanson Wade Limited is registered in England & Wales, number 06752216.
Registered Office: Eastcastle House, 27/28 Eastcastle Street, London, W1W 8DH.