Takatoshi Soga
![Takatoshi Soga Takatoshi Soga](https://macrophage-directed-therapies.com/wp-content/uploads/sites/109/2024/06/Takatoshi-Soga-150x150.png)
Company: United Immunity
Job title: Senior Vice President, Research
Seminars:
Overcoming Hostile Tumor Microenvironment With UI-102, a Pullulan Nanoparticle DDS-Encapsulated TLR7/8 Agonist That Actively Targets DCSIGN- Expressing M2-Like Tumor-Associated Macrophages 2:00 pm
UI-102 significantly enhanced the efficacy of PD-1 and PD-L1 inhibitors in murine tumor models that are treatment resistant to checkpoint inhibitors UI-102 promoted polarization of M2-like tumor-associated macrophages (TAMs) into M1 resulting in the conversion of refractory “cold” tumors onto “hot” ones and increased recruitment of CD8+ T cells and NK cells into tumors Pullulan…Read more
day: Conference Day One